Licorice root is one of the oldest herbal remedies on the planet, used across cultures for over 4,000 years. Its active compounds, particularly glycyrrhizin, have drawn increasing attention from modern researchers exploring everything from gut health to heart protection. Understanding the full range of licorice root benefits can help you decide whether this ancient herb deserves a place in your wellness routine.
1. May Support Digestive Comfort
One of the most well-known licorice root benefits is its traditional use for digestive complaints. Research suggests that compounds in licorice root may help soothe the stomach lining and ease symptoms of indigestion. Deglycyrrhizinated licorice, or DGL, is a specially processed form that removes most of the glycyrrhizin. This makes it gentler for regular digestive support. Some clinical evidence shows DGL may help with functional dyspepsia, a common condition involving chronic upper belly discomfort. If you experience occasional stomach upset, DGL supplements are widely available and considered a milder option. Talk to your healthcare provider before starting any new supplement regimen.
2. Offers Powerful Anti-Inflammatory Properties
Chronic inflammation plays a role in many modern diseases, from arthritis to heart disease. Licorice root contains compounds like glycyrrhizin and glycyrrhetinic acid that studies indicate possess notable anti-inflammatory effects. According to research published in PubMed, these licorice-derived compounds aid in treating inflammatory diseases including colitis and neuroinflammation. They appear to work by modulating key inflammatory pathways in the body. This makes licorice root a fascinating subject for ongoing research into natural anti-inflammatory strategies. Consider discussing licorice root with your doctor if inflammation is a concern for you.
3. Could Help Protect Heart Health
Heart disease remains the leading cause of death worldwide, so any natural support is worth exploring. Clinical evidence shows that licorice root extract may reduce certain risk factors tied to cardiovascular problems. One notable human study published in PubMed found that licorice root extract reduced plasma susceptibility to oxidation by 19% and increased LDL resistance to atherogenic modifications. These effects suggest licorice may help protect cholesterol from the damage that contributes to plaque buildup. While more large-scale studies are needed, these early findings are promising. A heart-healthy diet remains your best foundation, but licorice root may offer complementary support.
4. May Promote Healthy Cholesterol and Lipid Levels
Beyond protecting LDL from oxidation, licorice root may also influence overall lipid levels. Animal research suggests it could play a role in managing cholesterol and triglycerides. A study highlighted on PubMed found that licorice sprout extracts reduced lipid levels including cholesterol and triglycerides in rats, with no signs of cytotoxicity. The extracts also enhanced antioxidant enzyme levels, adding a layer of cellular protection. While animal studies don’t always translate directly to humans, these results are encouraging. Maintaining healthy lipid levels is a key strategy for long-term cardiovascular wellness.
5. Provides Antioxidant Protection
Free radicals damage cells and accelerate aging, making antioxidant intake genuinely important. Licorice root is rich in flavonoids and other polyphenols that act as natural antioxidants. Research suggests these compounds help neutralize oxidative stress throughout the body. The same animal studies showing lipid improvements also demonstrated enhanced antioxidant enzyme activity with licorice supplementation. This dual action on lipids and oxidative stress is part of what makes the herb so intriguing to researchers. Adding antioxidant-rich foods and herbs to your diet is a practical step anyone can take toward better long-term health.
6. Supports Oral Health
Your mouth is a gateway to overall health, and licorice root may help keep it in good shape. Studies indicate that compounds in licorice root, especially glycyrrhizin, exhibit antimicrobial properties effective against oral pathogens. According to a review on PubMed, licorice shows anti-inflammatory, antimicrobial, and immunomodulatory effects beneficial for oral diseases including caries, periodontitis, and candidiasis. Some natural toothpastes and mouthwashes already include licorice root extract. This is one of the more accessible licorice root benefits to incorporate into daily life. Look for oral care products that list licorice root as an active ingredient.
7. May Help With Weight Management
Maintaining a healthy weight is a common goal, and licorice root may offer modest support. The same human study examining cardiovascular effects found that licorice root extract also decreased body weight, BMI, and visceral fat in participants. Visceral fat, the deep belly fat surrounding organs, is particularly linked to metabolic disease. While licorice root is not a magic weight loss solution, these findings suggest it could play a complementary role alongside diet and exercise. Researchers believe the antioxidant and anti-inflammatory properties may improve metabolic function. Always pair any supplement with sustainable lifestyle habits for the best results.
8. Could Soothe Sore Throats and Upper Respiratory Issues
Licorice root tea has been a go-to remedy for sore throats across many cultures. Research suggests that its demulcent properties help coat and soothe irritated mucous membranes. Some studies have even explored licorice gargle solutions before medical procedures involving throat intubation. Results indicate that pre-treatment with licorice may reduce post-procedure throat soreness. The herb’s anti-inflammatory action likely contributes to this soothing effect. Sipping on licorice root tea during cold season is a simple and pleasant way to explore this potential benefit for yourself.
9. May Support Skin Health
Glabridin, a compound found in licorice root, has attracted attention in dermatology circles. Research suggests it may help brighten skin and reduce the appearance of dark spots by inhibiting tyrosinase, an enzyme involved in melanin production. Its anti-inflammatory properties also make it useful for calming redness and irritation. Many skincare products now feature licorice root extract as a gentle, plant-based active ingredient. Studies indicate it may benefit conditions like eczema and mild hyperpigmentation. If you prefer natural skincare, look for serums or creams containing licorice root extract as a key component.
10. Shows Promise for Immune System Support
A well-functioning immune system is your body’s first line of defense. Licorice root contains compounds with immunomodulatory properties, meaning they may help regulate rather than simply boost immune function. Research suggests glycyrrhizin can influence the activity of certain immune cells and cytokines. This balanced approach to immune support is especially interesting because overactive immunity drives autoimmune conditions. Early studies show promise, though much of the evidence remains preclinical. Incorporating licorice root as part of a broader healthy lifestyle may offer gentle immune support, but always check with your doctor first, especially if you take medications.
Licorice root is far more than a flavoring agent — it is a complex herb with a wide range of potential health applications supported by growing scientific evidence. From heart health and inflammation to oral care and skin support, these licorice root benefits are worth exploring with your healthcare provider. Start by discussing whether a licorice root supplement or topical product might complement your current wellness plan.
Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before making health decisions.
